Mahalanobis , confronted Haldane about both the hunger strike and the unbudgeted banquet, Haldane resigned from his post in February , and moved to a newly established biometry unit in Odisha.
Haldane took Indian citizenship;  he was interested in Hinduism and became a vegetarian. Perhaps one is freer to be a scoundrel in India than elsewhere. So one was in the U. A in the days of people like Jay Gould , when in my opinion there was more internal freedom in the U. A than there is today. The "disgusting subservience" of the others has its limits. The people of Calcutta riot, upset trams, and refuse to obey police regulations, in a manner which would have delighted Jefferson.
I don't think their activities are very efficient, but that is not the question at issue. When on 25 June he was described in print as a " Citizen of the World " by Groff Conklin , Haldane's response was as follows: . No doubt I am in some sense a citizen of the world.
But I believe with Thomas Jefferson that one of the chief duties of a citizen is to be a nuisance to the government of his state. As there is no world state, I cannot do this. On the other hand, I can be, and am, a nuisance to the government of India, which has the merit of permitting a good deal of criticism, though it reacts to it rather slowly. I also happen to be proud of being a citizen of India, which is a lot more diverse than Europe, let alone the U.
A, the U. R or China, and thus a better model for a possible world organisation. It may of course break up, but it is a wonderful experiment. So, I want to be labeled as a citizen of India. Shortly before his death from cancer, Haldane wrote a comic poem while in the hospital, mocking his own incurable disease.
It was read by his friends, who appreciated the consistent irreverence with which Haldane had lived his life. The poem first appeared in print in 21 February issue of the New Statesman , and runs:  . I know that cancer often kills, But so do cars and sleeping pills; And it can hurt one till one sweats, So can bad teeth and unpaid debts. A spot of laughter, I am sure, Often accelerates one's cure; So let us patients do our bit To help the surgeons make us fit. Haldane died on 1 December in Bhubaneswar. He willed that his body be used for study at the Rangaraya Medical College , Kakinada.
My body has been used for both purposes during my lifetime and after my death, whether I continue to exist or not, I shall have no further use for it, and desire that it shall be used by others. Its refrigeration, if this is possible, should be a first charge on my estate. Following his father's footsteps, Haldane's first publication was on the mechanism of gaseous exchange by haemoglobin.
In , with G. Briggs , Haldane derived a new interpretation of the enzyme kinetics law described by Victor Henri in , different from the Michaelis—Menten equation. Leonor Michaelis and Maud Menten assumed that enzyme catalyst and substrate reactant are in fast equilibrium with their complex, which then dissociates to yield product and free enzyme. The Briggs—Haldane equation was of the same algebraic form; but their derivation is based on the quasi- steady state approximation, which is the concentration of intermediate complex or complexes does not change.
As a result, the microscopic meaning of the "Michaelis Constant" K m is different. Although commonly referring to it as Michaelis—Menten kinetics, most of the current models typically use the Briggs—Haldane derivation. With his sister Naomi Mitchison , Haldane started investigating Mendelian genetics in , used guinea pigs and mice , publishing Reduplication in mice in  the first demonstration of genetic linkage in mammals , showing that certain genetic traits tend to be inherited together as was later discovered, because of their proximity on chromosomes. Crow called it "the most important science article ever written in a front-line trench".
In his essay On Being the Right Size he outlines Haldane's principle , which states that the size very often defines what bodily equipment an animal must have: "Insects, being so small, do not have oxygen-carrying bloodstreams. What little oxygen their cells require can be absorbed by simple diffusion of air through their bodies.
But being larger means an animal must have complicated oxygen pumping and distributing systems to reach all the cells. Haldane introduced the modern concept of abiogenesis in an eight-page article titled The origin of life, in the Rationalist Annual in ,  describing the primitive ocean as a "vast chemical laboratory" containing a mixture of inorganic compounds — like a "hot dilute soup" in which organic compounds could have formed.
Under the solar energy the anoxic atmosphere containing carbon dioxide , ammonia and water vapour gave rise to a variety of organic compounds, "living or half-living things". The first molecules reacted with one another to produce more complex compounds, and ultimately the cellular components.
At some point a kind of "oily film" was produced that enclosed self-replicating nucleic acids, thereby becoming the first cell. Bernal named the hypothesis biopoiesis or biopoesis , the process of living matter spontaneously evolving from self-replicating but lifeless molecules. Haldane further hypothesised that viruses were the intermediate entities between the prebiotic soup and the first cells. He asserted that prebiotic life would have been "in the virus stage for many millions of years before a suitable assemblage of elementary units was brought together in the first cell.
The gained some empirical support in with the classic Miller—Urey experiment. Since then, the primordial soup theory Oparin—Haldane hypothesis has become prevalent in the study of abiogenesis. In , Haldane proposed that genetic disorders in humans living in malaria -endemic regions provided a phenotype with immunity to blood-borne haemophiles.
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He noted that mutations expressed in red blood cells, such as sickle-cell anemia and various thalassemias , were prevalent only in tropical regions where malaria has been endemic. He further observed that these were favourable traits for natural selection which protected individuals from receiving malarial infection. Allison in He was one of the three major figures to develop the mathematical theory of population genetics , along with Ronald Fisher and Sewall Wright.
He thus played an important role in the modern evolutionary synthesis of the early 20th century. He re-established natural selection as the central mechanism of evolution by explaining it as a mathematical consequence of Mendelian inheritance. Haldane's book, The Causes of Evolution , summarised these results, especially in its extensive appendix.
A pragmatic dialectical-materialist Marxist , he wrote many articles for the Daily Worker. In On Being the Right Size , he wrote: "while nationalization of certain industries is an obvious possibility in the largest of states, I find it no easier to picture a completely socialized British Empire or United States than an elephant turning somersaults or a hippopotamus jumping a hedge. In , he proclaimed enthusiastically that "I think that Marxism is true. He was pressed to speak out about the rise of Lysenkoism and the persecution of geneticists in the Soviet Union as anti-Darwinist and the political suppression of genetics as incompatible with dialectical materialism.
He shifted his polemic focus to the United Kingdom, criticizing the dependence of scientific research on financial patronage. In he wrote about the Soviet trial of his friend and fellow geneticist Nikolai Vavilov :. The controversy among Soviet geneticists has been largely one between the academic scientist, represented by Vavilov and interested primarily in the collection of facts, and the man who wants results, represented by Lysenko. It has been conducted not with venom, but in a friendly spirit. Lysenko said in the October discussions of : 'The important thing is not to dispute; let us work in a friendly manner on a plan elaborated scientifically.
Let us take up definite problems, receive assignments from the People's Commissariat of Agriculture of the USSR and fulfil them scientifically. Soviet genetics, as a whole, is a successful attempt at synthesis of these two contrasted points of view. By the end of the Second World War Haldane had become an explicit critic of the regime.
He left the party in , shortly after considering standing for Parliament as a Communist Party candidate. He continued to admire Joseph Stalin , describing him in as "a very great man who did a very good job". Haldane was the first to have thought of the genetic basis for human cloning , and the eventual artificial breeding of superior individuals. For this he introduced the terms "clone" and "cloning",  modifying the earlier "clon" which had been used in agriculture since the early 20th century from Greek klon , twig.
He said:  . It is extremely hopeful that some human cell lines can be grown on a medium of precisely known chemical composition. Perhaps the first step will be the production of a clone from a single fertilized egg, as in Brave New World On the general principle that men will make all possible mistakes before choosing the right path, we shall no doubt clone the wrong people [like Hitler] Assuming that cloning is possible, I expect that most clones would be made from people aged at least fifty, except for athletes and dancers, who would be cloned younger.
They would be made from people who were held to have excelled in a socially acceptable accomplishment. His essay Daedalus; or, Science and the Future introduced the term ectogenesis for the concept of what is later known as in vitro fertilisation test tube babies. He envisioned ectogenesis as a tool for creating better individuals eugenics. His book, A. Air Raid Precautions combined his physiological research into the effects of stress upon the human body with his experience of air raids during the Spanish Civil War to provide a scientific account of the likely effects of the air raids that Britain was to endure during the Second World War.
Richards , and H. Wells , Haldane was accused by C. Lewis of scientism. Haldane criticised Lewis and his Ransom Trilogy for the "complete mischaracterisation of science, and his disparagement of the human race". In , in a talk given in Cambridge titled "Science and the Future", Haldane, foreseeing the exhaustion of coal for power generation in Britain, proposed a network of hydrogen -generating windmills.
He envisioned ectogenesis as a tool for creating better individuals eugenics. His book, A. Air Raid Precautions combined his physiological research into the effects of stress upon the human body with his experience of air raids during the Spanish Civil War to provide a scientific account of the likely effects of the air raids that Britain was to endure during the Second World War. Richards , and H. Wells , Haldane was accused by C. Lewis of scientism.
Haldane criticised Lewis and his Ransom Trilogy for the "complete mischaracterisation of science, and his disparagement of the human race". In , in a talk given in Cambridge titled "Science and the Future", Haldane, foreseeing the exhaustion of coal for power generation in Britain, proposed a network of hydrogen -generating windmills.
This is the first proposal of the hydrogen-based renewable energy economy. In his An Autobiography in Brief , published shortly before his death in India, Haldane named four close associates as showing promise to become illustrious scientists: T. Haldane was elected a Fellow of the Royal Society in In , he received the Darwin Medal from the Royal Society. Haldane was parodied as "the biologist too absorbed in his experiments to notice his friends bedding his wife" by his friend Aldous Huxley in the novel Antic Hay From Wikipedia, the free encyclopedia.
British geneticist and evolutionary biologist. Oxford , England. Bhubaneswar , India. United Kingdom United States India. Charlotte Franken m. Helen Spurway m. Darwin—Wallace Medal Darwin Medal Biology Biostatistics. Further information: Prebiotic soup. Further information: Modern synthesis 20th century.
Biographical Memoirs of Fellows of the Royal Society. Journal of Genetics. A to Z of Biologists. Archived from the original on 7 March In John Burdon Sanderson Haldane ed. Oxford: Oxford University Press. Archived from the original on 8 March Haldane — : centennial appreciation of a polymath". American Journal of Human Genetics. Cambridge, Mass. Journal of the History of Biology. Archived from the original on 27 July Retrieved 12 July Haldane: A Legacy in Several Worlds".
Archived from the original on 22 February Haldane — ". Oxfordshire Blue Plaques Board. Retrieved 17 February The Journal of Physiology. The London Gazette Supplement. The 10, Year Explosion. Archived from the original on 9 June Retrieved 5 May New College, Oxford. Archived from the original on 25 April Retrieved 15 April FRS ". Archived from the original on 4 March UCL Archives. University College London. Archived from the original on 2 March Retrieved 3 February Investigative Genetics. H New York: Broadway Books, Dronamraju Notes and Records of the Royal Society of London.
Dordrecht: Springer. Archived PDF from the original on 10 September The Orwellian World of Jehovah's Witnesses. Toronto: University of Toronto Press. Archived from the original on 12 March Haldane's last years: his life and work in India — ". Betrayed by Nature: The War on Cancer. Vigyan Prasar Science Portal.
Archived from the original on 14 April Retrieved 19 February Krishna Spice in science. Dehli: Pustak Mahal. Archived from the original on 21 September Retrieved 1 February The Biochemical Journal. Archived from the original on 18 October Haldane, with special reference to Human Genetics in India".
Indian Journal of Human Genetics. Haldane, —". Bibcode : Sci Dictionary of Scientific Principles. Cold Spring Harbor Perspectives in Biology.
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New Brunswick, N. Archived from the original on 26 February Retrieved 18 February Department of Chemistry, University of Oxford. When the going gets particularly tough, the Pardeys seem to gather people around and celebrate. As a result, Lin and Larry have been having a wonderful life together, one well worth telling about. With it, Lin the storyteller has bridged the divide between sailors and landsmen and will touch readers of every inclination. Stop right there, guys! The fact is that three-fourths of the folks who pre-ordered the book were men. A number of gents are buying the newly released book as a gift to wives or partners, to share with them the joys and realities of living aboard a cruising boat.
The 25 women contributors to the newly released book candidly share their fears and adventures with vulnerability, enthusiasm, practicality and humor. Others have sailed around the world. Favors herself has 20, miles of cruising experience, including two 6,miles loops aboard her boat, Kismet. Anchored in experience, both books address questions common to those considering sailing off into the sunset.
My learning curve would have been much less steep if Fundamentals of Model Boat Building had been available. Along the way, they discuss the research and planning that is required to produce an accurate model. They introduce the materials, methods, and techniques used to produce the model form and its intricate details.
They describe the choices available for finishing the model, and they end the book with a nice photo gallery showing several examples of completed models. I looked at this book from the perspective of a fellow model boat builder and found the explanations and terminology easy to follow. Others who build models or might be interested in doing so would do well to add Fundamentals of Model Boat Building to their reference library.
When writing tools were handed out, David was apparently issued a lifetime supply of run-on sentences and overused adjectives but a dearth of periods. Bucking the Tide is a self-published book in need of a copy editor at its helm. Um, note the subtitle. Sentences running 60 to 70 words are common. Chapter 6 is 91 pages in length — nearly half the book. The sheer quantity of words lashed together, along with an onslaught of adjectives, creates a barrage of verbiage.
A crisper telling would have been a blessing. And sincere. His observations are keen and his descriptions of local folk and scenes are a pleasure to visualize from the comfort of couch or cockpit. David maintains, from experience, that if people know where to look, the raw materials of extraordinary experiences can be found close at hand.
The book contains a selection of photographs from the trip along the New England and Fundy coasts along with a number of well-done illustrations. Several chapters end with an inspiring quote from Thoreau or other Wise Ones. Readers who can get past the grammatical issues are likely to enjoy the story. Pack the lunch. Apply the sunblock. Many of the essays were previously published in the Catboat Association Bulletin.
For the most part, I found the stories to be enjoyable and lightly humorous, such as the alcohol stove that caught fire and had to be doused, then buried at sea or the overweight old gent whose attempts to climb back on board after a skinny-dipping excursion provided a sea of laughter for the other two crewmembers. Though the reader can readily glean little tidbits about the specific sailing characteristics of catboats, this is not a book about sailing catboats. At only 7 by 7 inches, this book is relatively small. It is also hardbound and too big to put into anything smaller than a large coat pocket or purse.
Other than that, Catboat Tales might be great to carry around for those times when you have two or three minutes to spend while waiting for a child or spouse. My only wish was for the book to be longer. It has large print and, with 32 photos and illustrations taking up page space, at only 70 pages, it is quite short.
A fast reader could easily read the whole thing in less than 30 minutes. I did find a couple of the photos to be striking and, if enlarged, would probably make great wall prints. At the opening of the book, Hugh MacMillan who has been a past contributor to Good Old Boat magazine has just gotten a reprieve from a potentially terminal cancer diagnosis, and while he relishes the fact that he now has a longer lifespan ahead of him, he also realizes that life is finite and he needs to act on that fact while he can.
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The author is a gifted storyteller. His tendency to use bizarre plot devices for example, a genie in a bottle and a sea monster are explained later in the book as his usual way of embellishing stories to make them more entertaining to the youngsters in his family. Completely dismissing the book on that basis would be a shame, as the author has much to say and it is worth paying attention to. If the reader can ignore or, if he or she so chooses — embrace the insertion of genies, etc. It will be interesting to learn what he gathered from those voyages as well.
Here is an entire book of them. This book there is also a video contains almost quick fixes, devices and gadgets that the good Captain has installed on his boat, Ternabout. The book is divided into 11 chapters: The Boat; Cabin, including gear holders and improving ventilation; Galley including recipes! Capt'n Pauley describes the problem, lays out several possible solutions, then explains what he did in his easy to understand style. His article on mast raising systems, for example, goes into several different rigs and includes cautions about dealing with the hazards of handling the ungainly weight aloft.
The book is spiral bound with plastic laminate covers—an advantage, since it will lie open on a workbench for easy reference. There are plenty of photos and drawings to explain the devices being proposed. This book is a flipper—one does not read it cover to cover so much as flip through it, checking out Pauley's ideas and getting inspiration for one's own boat projects. Here he is in his own book, telling the story of his circumnavigation aboard Low Key , a 33' sloop.
Captain Woody tells his story with the same humorous, down-to-earth sea? His sketches and sagas, told in his distinctive style, of adventures ashore bring the book to life. Hey, the sailing parts are great, too, but Woody and crew stopped to smell the hibiscus. And quaff a few ales. It makes you want to be aboard the next time Woody sails out of the harbor.
And it makes you drool over the eight pages of color photos that supplement the word pictures. Life slowed down and quality increased. The world opened up and revealed a thousand great experiences. I was back in the land of showering off the swim step, hiking waterfalls, getting to know the locals and enjoying three-stop shopping: bakery, fruit stand, vegetable market. The art of tying knots is many centuries old. From sailors to mountaineers, from riggers to rescue workers, knots have been intimate companions for many professions.
What better way to edify this old art than to have it condensed in one volume that illustrates every aspect of the art of making knots. Lindsey Philpott, a rigger and teacher of contemporary marlinespike seamanship as well as a forensic expert of knot analyses in criminal cases, has written a marvelous book that captures the art of tying. The volume is beautifully designed and makes a fabulous piece of art that deserves to occupy any coffee table. The book consists of a wonderful cornucopia of rare and exotic decorative knots. It contains 1, colored illustrations of every existing knot, starting with flat knots and ending with yacht wheel marker knots.
In addition, it covers every knot that ever existed from all over the world, making it a distinct treasure chest saturated with useful information for anyone who harbors interest in this artisanship. This volume is comprehensive, yet clear and precise.
It is intense, yet fun and entertaining. From braids to plaits to sinnets, this book will take the reader on a panoramic journey to the land of knots through step-by-step instructions for tying hundred of types of knots both useful and artistic. It will also furnish the reader with directions to find the correct tools, materials, and the specialty shops that carry them. The chapters flow smoothly and deliver a significant amount of information that covers the whole gamut of knot land. It also contains a terrific glossary and a clear index that will help you find the knot of your choice.
The book is a terrific and thorough reference on knots, and will make a great read for sailors, mountaineers, rock climbers, firefighters, rescue workers, linesmen, riggers, campers, and anyone who has an interest in tying knots. It will even arouse interest in the knot indifferent.
Larke, El Capitan And The Theory Of Everything
The United States Coast Guard has rescued more than a million people since its founding over years ago. Most folks know about the Coast Guard rescue services. Boaters generally also know that the Coasties provide boating safety courses, license mariners, and inspect recreational, commercial, and fishing vessels. Not to mention flying around in those orange helicopters, making their presence generally known.
For example, their duties are not blue water only. They are also responsible for icebreaking operations on the Great Lakes. They cover a huge area. The U. Of particular interest is the training of the helicopter pilots; the mechanics who maintain the choppers, run the hoists, and direct the pilots during a rescue; and the rescue swimmers.
A pilot based in Florida and a swimmer stationed in Texas can operate as smoothly as a crew that has been flying rescues together for years. The flow of the book, however, is hindered due to a preponderance of lengthy sentences overflowing with punctuation. In addition, it is somewhat disconcerting in a nonfiction book written in the third person to have Helvarg periodically insert himself onto the pages.
It is particularly jarring when that commentary consists of frequently unflattering opinions about government agencies, prominent officials, and the other branches of the military. Nevertheless, this book offers some great information. Ignore the opinions and enjoy this tribute to the men and women who respond to more than distress calls every day. This is a magnificent little book for anybody who wants to do his own sail repair or fancy canvas work.
Rosenow learned his nautical skills growing up in Marstrand, Sweden, raced and sailed cruising boats, and later apprenticed himself to master sailmaker Gunnar Andersson. In the s, while continuing to cruise, he became a columnist for Sail magazine, where he is remembered for his award-winning pencil and watercolor illustrations. Rosenow divides The Ditty Bag Book into two parts, tools and processes, and begins with the absolute basics. He clearly explains the craft of worming, parceling, and serving rope or wire rigging to protect against dampness and chafe as well as heaving tools and wire locks.
Finally, he shows you how to sew in rings and grommets and goes over traditional and wire rope, tape and canvas. All of this is beautifully illustrated by his drawings on the use of the tools. According to author Robert Engel, " Sail Tales is about the adventures a humble sailboat owner had over the years. The book is organized into seven sections, mostly in chronological order. The first four sections are organized according to the progressively larger boats owned and sailed at the time, with a short history of each boat.
The rest take place in Virginia Beach and south into Florida. Bob repeatedly attempts to describe the Long Island area, but any reader not intimately familiar with the north end of Long Island will soon wish he had included a map illustration in the book. For the most part, the stories are interesting and often humorous.
I felt that a few of the stories were not very well composed, even amateurish, though the underlying story was good. The lack of an editor became rather annoying and seems strange, considering the author is a retired English teacher. The stories are all short — most are only three or four pages. Laura S. This was an exciting place, especially for a young, ambitious man like Edward Marshall who epitomized the entrepreneurial spirit that made America a haven for him and those of his ilk.
With dreams of becoming a shipbuilder, merchant, and businessman, he is well on his way to establishing a reputation as an honest, hardworking individual, learning and earning as he absorbs all he can to make his dream come true. We first meet Edward as a young boy whose father had left his wife and their prosperous sugar plantation in Barbados years earlier to live a life of adventure as a pirate. Edward resented his lineage and the trouble it caused him, so when Reverend Eubanks invited the nine-year-old to join him in his new assignment in Brunswick, in colonial Carolina, Edward jumped at the chance.
The story picks up fifteen years later when we see Edward in early adulthood making a name for himself as an aspiring entrepreneur in his adopted town, where he still seeks the advice of the aging Reverend Eubanks, whose friendship Edward still cherishes. Some of the characters develop quite nicely in the heart of the novel, but they seem to disappear when they could have been a larger feature and made a heftier contribution to the story, thereby adding to the intrigue.